WebNov 13, 2024 · Dolutegravir (DTG), an integrase strand transfer inhibitor, has better efficacy, tolerability and durability than non-nucleoside reverse transcriptase inhibitor (NNRTI)-based first-line regimens [].DTG is recommended by the World Health Organization (WHO) as the preferred first- and second-line antiretroviral therapy (ART) [2,3,4,5].DTG induces rapid … WebJul 28, 2024 · ART, antiretroviral therapy; ATT, anti-tuberculosis treatment; AZT, zidovudine; DKA, diabetic ketoacidosis; DNA, deoxyribonucleic acid; DTG, dolutegravir; EFV, efavirenz; GAD, glutamic acid decarboxylase; HIV, human immunodeficiency virus; INSTIs, integrase strand transfer inhibitors; NVP, nevirapine; NRTIS, nucleoside/tide …
Hyperglycemia After Dolutegravir-Based Antiretroviral Therapy
Webdolutegravir (DTG) in place of efavirenz—that is, TLD, with the “D” standing for dolutegravir. This recommended regimen is a combination of two NRTIs and one INSTI. TLD is a fixed … WebFeb 17, 2024 · Receipt of any other antiretroviral therapy other than DTG and 2 NRTI within 28 days prior to study entry. Receipt of TAF within 28 days prior to study entry. Documented resistance that may confer reduced susceptibility to DTG, at any time prior to study entry. This includes the following INSTI mutations: Q148 substitutions, T66A, L74I/M, E138A ... chair for pool shelf
Table 6. What to Start: Initial Antiretroviral Regimens During ...
WebFeb 26, 2024 · Background The objective of this study was to assess the durability of response of dolutegravir (DTG) as an antiretroviral core agent by comparing its efficacy and safety with other recommended or commonly used core agents up to 96-weeks (W96). Methods A previously published systematic review was updated to identify phase 3/4 … WebTake an open minded approach to client wellness and consider work life, family traditions, cultural and spiritual beliefs when providing counseling. Utilize a strengths based … WebDolutegravir impact on bone has been evaluated in the GS-US-380-1489 study on antiretroviral therapy-naive patients, in which similar small decrease in hip and lumbar spine BMD were evidenced both in patients on bictegravir (BIC)/TAF/FTC and DTG/ABC/3TC. 42 Similar and small increases from baseline to week 48 were seen in hip and lumbar spine ... chair for reading in bed