Simvastatin clarithromycin interaction
Webb19 okt. 2024 · If clarithromycin is necessary, we recommend (a) avoiding co-administration with simvastatin, lovastatin or atorvastatin; (b) withholding or dose-reducing … WebbSimvastatin: erythromycin & clarithromycin are contraindicated. If treatment with erythromycin & clarithromycin cannot be avoided suspend simvastatin for duration of antibiotic course and for 7 days after last antibiotic dose. Use of a statin that is not dependent on CYP3A metabolism (e.g. fluvastatin) can be considered.
Simvastatin clarithromycin interaction
Did you know?
WebbClinician Explanation Contraindicated Never use this combination of drugs because of high risk for dangerous interaction clarithromycin oral and simvastatin oral clarithromycin … Webb1 aug. 2014 · The drug-drug interaction between simvastatin and clarithromycin was modeled simultaneously with a parent-metabolite model for clarithromycin and a one-compartment model for simvastatin linked to ...
Webb62 interactions Amiodarone Amiodarone is predicted to increase the exposure to Colchicine. Manufacturer advises avoid P-glycoprotein inhibitors or adjust Colchicine dose. Severity: Severe Evidence: Theoretical Apalutamide Apalutamide is predicted to decrease the exposure to Colchicine. Manufacturer advises monitor. Severity: Mild Evidence: Study WebbCardiac patients with weak immune system are susceptible to bacterial infections. Their prescriptions frequently contain simvastatin and clarithromycin together. The objective of present project was to assess the potential interaction between simvastatin and clarithromycin by evaluating the clarithr …
WebbWhen co-administered with simvastatin, clarithromycin can significantly increase simvastatin plasma concentration levels, thereby, increase the risk of rhabdomyolysis. At present, pharmacokinetic data of the interaction between both drugs are available. Webb27 apr. 2024 · An 81-year-old man developed rhabdomyolysis and drug-induced liver injury (DILI) following concomitant administration of simvastatin and clarithromycin. The man …
Webb5 feb. 2024 · Certain drugs can interact with atorvastatin (Lipitor) and increase its side effects. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral contraceptives containing norethindrone or ethinyl estradiol, digoxin, rifampin, and colchicine. What foods should be avoided when …
WebbSchwere Interaktion: Simvastatin und Clarithromycin 4 min merken Schwere Interaktion: Simvastatin und Clarithromycin Bei schwerwiegenden Interaktionen muss mit dem verordnenden Arzt Rücksprache gehalten werden. So auch bei der Kombination von Simvastatin und Clarithromycin. Bild: Schelbert / PTAheute birch bifold doorsWebb11 dec. 2014 · Simvastatin and atorvastatin: interactions Many important interactions for simvastatin (Zocor) and atorvastatin relate to drugs that inhibit or induce metabolism via … birch bifold closet doorsWebbThe most common adverse effects of clarithromycin include mild nausea, vomiting, abdominal discomfort, and diarrhoea. Consider pseudomembranous colitis if a person develops severe diarrhoea during or after treatment with clarithromycin. For more information, see the CKS topic on Diarrhoea - antibiotic associated. birch birds boxed mugWebbAtorvastatin is the generic name for a widely prescribed statin medication, originally prescribed under the brand name Lipitor. Atorvastatin oral tablet dosage and frequency will depend upon several factors, the most important being the medical condition it is … birch birdhouseWebbSimvastatin 122 interactions Acipimox Acipimox is predicted to increase the risk of rhabdomyolysis when given with Simvastatin. Manufacturer advises caution. Severity: … birch betula platyphylla fermentedWebb11 dec. 2014 · The changes include contraindications to concomitant use with certain medicines and maximum dose recommendations when simvastatin is taken with a … birch biome seedWebb23 dec. 2014 · The antibiotic clarithromycin and cholesterol-lowering statins are some of the most widely prescribed drugs in the world. New research, however, has found that certain combinations of the two ... dallas cowboys christmas ornaments clearance